custom designed oligonucleotide microarray Search Results


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Pearson similarity index of donors over time and recurrent Clostridium difficile infection (RCDI) patients to donors. Samples were analyzed using a <t>DNA</t> <t>microarray.</t> A , Donors retained a high degree of similarity to their own samples over their donation time period. Donor 1 = 18 months; Donor 2 = 12 months; Donor 3 = 7 months ( B ) Percent similarity of the single fecal microbiota transplantation (FMT) recipient samples at those time points (1 = 1–4 weeks; 2 = 8–52 weeks post FMT [PFT]) to their respective donor. Following FMT, the similarity of the RCDI patients increased to more closely resemble the donors; **** P -value <.0001 calculated using paired t -test; *** P -value =.0005 calculated using Mann–Whitney test. C , Percent similarity of the repeated FMT recipient samples at those time points to the respective donor of the most recent FMT (PFT1: 1–2 weeks; PFT2: 3–28 weeks); * P -value <.05; ** P -value <.005 both calculated using Mann–Whitney test. Whiskers denote mean with the standard deviation. Abbreviation: BFT, before FMT.
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SuperArray Bioscience Corporation customized mouse oligo gearray microarray membranes with 113 oligonucleotide probes representing neurotrophin associated genes
Pearson similarity index of donors over time and recurrent Clostridium difficile infection (RCDI) patients to donors. Samples were analyzed using a <t>DNA</t> <t>microarray.</t> A , Donors retained a high degree of similarity to their own samples over their donation time period. Donor 1 = 18 months; Donor 2 = 12 months; Donor 3 = 7 months ( B ) Percent similarity of the single fecal microbiota transplantation (FMT) recipient samples at those time points (1 = 1–4 weeks; 2 = 8–52 weeks post FMT [PFT]) to their respective donor. Following FMT, the similarity of the RCDI patients increased to more closely resemble the donors; **** P -value <.0001 calculated using paired t -test; *** P -value =.0005 calculated using Mann–Whitney test. C , Percent similarity of the repeated FMT recipient samples at those time points to the respective donor of the most recent FMT (PFT1: 1–2 weeks; PFT2: 3–28 weeks); * P -value <.05; ** P -value <.005 both calculated using Mann–Whitney test. Whiskers denote mean with the standard deviation. Abbreviation: BFT, before FMT.
Customized Mouse Oligo Gearray Microarray Membranes With 113 Oligonucleotide Probes Representing Neurotrophin Associated Genes, supplied by SuperArray Bioscience Corporation, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Shanghai Biochip Co. Ltd agilent custom 60-mer oligonucleotide microarrays
Pearson similarity index of donors over time and recurrent Clostridium difficile infection (RCDI) patients to donors. Samples were analyzed using a <t>DNA</t> <t>microarray.</t> A , Donors retained a high degree of similarity to their own samples over their donation time period. Donor 1 = 18 months; Donor 2 = 12 months; Donor 3 = 7 months ( B ) Percent similarity of the single fecal microbiota transplantation (FMT) recipient samples at those time points (1 = 1–4 weeks; 2 = 8–52 weeks post FMT [PFT]) to their respective donor. Following FMT, the similarity of the RCDI patients increased to more closely resemble the donors; **** P -value <.0001 calculated using paired t -test; *** P -value =.0005 calculated using Mann–Whitney test. C , Percent similarity of the repeated FMT recipient samples at those time points to the respective donor of the most recent FMT (PFT1: 1–2 weeks; PFT2: 3–28 weeks); * P -value <.05; ** P -value <.005 both calculated using Mann–Whitney test. Whiskers denote mean with the standard deviation. Abbreviation: BFT, before FMT.
Agilent Custom 60 Mer Oligonucleotide Microarrays, supplied by Shanghai Biochip Co. Ltd, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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Pearson similarity index of donors over time and recurrent Clostridium difficile infection (RCDI) patients to donors. Samples were analyzed using a DNA microarray. A , Donors retained a high degree of similarity to their own samples over their donation time period. Donor 1 = 18 months; Donor 2 = 12 months; Donor 3 = 7 months ( B ) Percent similarity of the single fecal microbiota transplantation (FMT) recipient samples at those time points (1 = 1–4 weeks; 2 = 8–52 weeks post FMT [PFT]) to their respective donor. Following FMT, the similarity of the RCDI patients increased to more closely resemble the donors; **** P -value <.0001 calculated using paired t -test; *** P -value =.0005 calculated using Mann–Whitney test. C , Percent similarity of the repeated FMT recipient samples at those time points to the respective donor of the most recent FMT (PFT1: 1–2 weeks; PFT2: 3–28 weeks); * P -value <.05; ** P -value <.005 both calculated using Mann–Whitney test. Whiskers denote mean with the standard deviation. Abbreviation: BFT, before FMT.

Journal: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America

Article Title: Fecal Microbial Transplants Reduce Antibiotic-resistant Genes in Patients With Recurrent Clostridium difficile Infection

doi: 10.1093/cid/ciw185

Figure Lengend Snippet: Pearson similarity index of donors over time and recurrent Clostridium difficile infection (RCDI) patients to donors. Samples were analyzed using a DNA microarray. A , Donors retained a high degree of similarity to their own samples over their donation time period. Donor 1 = 18 months; Donor 2 = 12 months; Donor 3 = 7 months ( B ) Percent similarity of the single fecal microbiota transplantation (FMT) recipient samples at those time points (1 = 1–4 weeks; 2 = 8–52 weeks post FMT [PFT]) to their respective donor. Following FMT, the similarity of the RCDI patients increased to more closely resemble the donors; **** P -value <.0001 calculated using paired t -test; *** P -value =.0005 calculated using Mann–Whitney test. C , Percent similarity of the repeated FMT recipient samples at those time points to the respective donor of the most recent FMT (PFT1: 1–2 weeks; PFT2: 3–28 weeks); * P -value <.05; ** P -value <.005 both calculated using Mann–Whitney test. Whiskers denote mean with the standard deviation. Abbreviation: BFT, before FMT.

Article Snippet: DNA was extracted and analyzed on a custom oligonucleotide-based DNA microarray containing 370 probes targeting 354 ABR genes (Lallemand Health Solutions, Montreal, Canada).

Techniques: Infection, Microarray, Transplantation Assay, MANN-WHITNEY, Standard Deviation